Parn and Samberg are back.

He’s mean and green…

Musical guest Usher performs his song “Scream.”

In honor of Mother’s Day, Will Ferrell wants to share some special words dedicated to his mom, straight from his mouth hole.

After President Obama pays a visit Joe Biden in his room, the vice president confides in his secret friend, George.

When a cold bug infiltrates your home, rid those awful sneezes with Nasaflu.

The funky candidates running for the mayor of Funkytown have to answer some tough questions from their funky constituents.

ESPN’s coverage of a women’s golf coverage is interrupted with news of OJ Simpson on the run and frequent advertisements for their …

Catch up on the headlines with Weekend Update anchor Seth Meyers.

Grady’s trip to Hawaii has him eager to share a variety of sex tips that will spice up your bedroom, regardless of age.

Seth has one question about the Time Magazine cover featuring a mother breast feeding a young boy.

Catch some of the hottest up-and-coming show tunes before they hit Broadway!

Musical guest Usher performs his song “Climax.”

A toast at an anniversary party gets sidetracked by several odd speakers.

Actor Liam Neeson gets in the cage with Nicolas Cage and has to answer some tough questions about his career.

Will hosts an all new SNL with musical guest Usher.

Jimmy Kimmel Live – The first part of Jimmy’s interview with Casey Wilson

Jimmy Kimmel Live’s YouTube channel features clips and …